A urethral stricture is a scar in or around the urethra, which can block the flow of urine, and is a result of inflammation, injury, or infection. Urethroplasty is a reconstructive surgery performed to correct urethral strictures. A urethroplasty involves surgically removing the stricture with reconnection and reconstruction with grafts.
Can urethral strictures be treated with medications?
No. Unfortunately scar tissue cannot be removed or bypassed without surgery.
What can occur if no treatment is taken?
The patient would have to continue to tolerate problems with urination. Urinary and/or testicular infections and stones can develop. Also, there is a risk that urinary retention may occur which can cause the bladder to enlarge and lead to kidney problems.
Are there other options?
Yes, treatment options for urethral stricture disease are varied and depend upon the length, location and degree of scar tissue associated with the stricture. In addition to urethroplasty, options include enlarging the stricture by gradual stretching (dilation) and cutting the stricture with a laser or knife through a telescope (urethrotomy). Repeated dilation can be considered but is not recommended. Long-term success rates are very low with repeated dilation, but this approach can be considered in patients who are not good candidates for reconstructive surgery (or do not want to undergo surgery).
After one dilation or urethrotomy, guidelines recommend proceeding to urethroplasty if the scar tissue returns. This is because the chance of success on a repeat dilation or urethrotomy is very low.
What are the success rates?
Because urethral strictures can recur at any time after surgery, patients should be monitored by a urologist. Success rates for urethroplasty are below:
What are the risks of surgery?
All surgeries carry a small risk of bleeding, infection, and injury to adjacent organs. Specific risks for urethral surgery are possible changes in sexual function. Although uncommon, poor erections, minor penile shortening, penile curvature, and changes in ejaculation may occur. Bladder control is rarely impacted, but your doctor will discuss with you if the location of your stricture might compromise urinary control.
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