Samuel A. Levine Professor of Medicine
Hersey Distinguished Professor of the Theory and Practice of Medicine
Harvard Medical School
Physician-in-Chief Emeritus
Brigham and Women’s Hospital
Joseph Loscalzo, MD, PhD, is currently the Samuel A. Levine Professor of Medicine and Hersey Distinguished Professor of the Theory and Practice of Medicine at Harvard Medical School as well as Physician-in-Chief Emeritus and former Chair of the Department of Medicine at Brigham and Women’s Hospital. Dr. Loscalzo received his AB degree, summa cum laude, his PhD in biochemistry, and his MD from the University of Pennsylvania. His clinical training was completed at Brigham and Women’s Hospital and Harvard Medical School, where he served as Resident and Chief Resident in medicine and Fellow in cardiovascular medicine.
After completing his training, Dr. Loscalzo joined the Harvard faculty and staff at Brigham and Women’s Hospital in 1984. He rose to the rank of Associate Professor of Medicine, Chief of Cardiology at the West Roxbury Veterans Administration Medical Center, and Director of the Center for Research in Thrombolysis at Brigham and Women’s Hospital. He joined the faculty of Boston University in 1994, first as Chief of Cardiology and, in 1997, Wade Professor and Chair of Medicine, Professor of Biochemistry, and Director of the Whitaker Cardiovascular Institute. He returned to Harvard and Brigham and Women’s Hospital in 2005 as the Hersey Professor of the Theory and Practice of Medicine, and Soma Weiss, MD, Distinguished Chair in Medicine at Harvard Medical School, Chair of the Department of Medicine, and Physician-in-Chief at Brigham and Women’s Hospital. He transitioned from Department Chair in 2022 to his current roles.
Dr. Loscalzo is recognized as an outstanding cardiovascular scientist, clinician, and teacher. He has received many awards, including the Clinician-Scientist Award, the Distinguished Scientist Award, the Research Achievement Award, a MERIT Award, the Paul Dudley White Award and the Gold Heart Award from the American Heart Association; a Research Career Development Award, a Specialized Center of Research in Ischemic Heart Disease Award, and a MERIT Award from the National Institutes of Health; the George W. Thorn Award for Excellence in Teaching at Brigham and Women’s Hospital, the Educator of the Year Award in Clinical Medicine from Boston University, and the William Silen Lifetime Achievement in Mentorship Award from Harvard Medical School; the Glaxo Cardiovascular Research Award, the Rector’s Silver Medal from the University of Rome, Sapienza, and the Outstanding Investigator Prize from the International Society for Heart Research; election to fellowship in the American Association for the Advancement of Science, and in the American Academy of Arts and Sciences; and election to the American Society for Clinical Investigation, the Association of American Physicians, and the National Academy of Medicine. Castle Connolly has named him one of America’s Top Doctors over many years.
He served as an associate editor of the New England Journal of Medicine for nine years, Chair of the Cardiovascular Board of the American Board of Internal Medicine, Chair of the Research Committee of the American Heart Association, Chair of the Scientific Board of the Stanley J. Sarnoff Society of Fellows for Research in the Cardiovascular Sciences, and Chair of the Board of Scientific Counselors of the National Heart, Lung, and Blood Institute of the National Institutes of Health. He is a former member of the Advisory Council of the National Heart, Lung, and Blood Institute, and a former member of the Council of Councils of the National Institutes of Health. He is currently Director of the NIH-funded Center for Accelerated Innovation (the Boston Biomedical Innovation Center), and of the NIH-funded Harvard Undiagnosed Disease Network program. He is also former Editor-in-Chief of Circulation, currently Editor-at-Large of the New England Journal of Medicine, and a current senior editor of Harrison’s Principles of Internal Medicine.
Dr. Loscalzo has been a visiting professor at many institutions, holds three honorary degrees, has authored or co-authored over 1,200 scientific publications (over 145,000 citations, h-index 174), has authored or edited 54 books, and holds 33 patents for his work in the field of nitric oxide, redox biology, and vascular biology. He is also the recipient of many grants from the NIH and industry for his work in the areas of vascular biology, thrombosis, atherosclerosis, and, more recently, systems biology over the past thirty years. His most recent work has established the field of network medicine, a paradigm-changing discipline that seeks to redefine disease and therapeutics from an integrated perspective using systems biology and network science.
