Brigham and Women’s Hospital’s
Center for Clinical Investigation (CCI)
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The CCI was established in 2000 to provide a full range of services and resources within a multi-disciplinary infrastructure, in order to maximize the ability of BWH to conduct clinical research. Over the past 8 years it has worked in concert with the GCRC to accomplish this task. Effective September 1, 2008, the CCI will assume all responsibilities currently residing in the GCRC and the expanded program established by the Harvard Clinical and Translational Science Center. It will be through the CCI that the BWH program will interface with Harvard’s CTSC.
The CCI will be comprised of the following services and facilities:
I. Participant and Clinical Interaction Resources (PCIR)
Inpatient Units: A 6-room Standard Bed Unit and a 5-room Intensive Physiologic Monitoring Unit provide space for a broad range of inpatient studies, available to BWH clinical researchers. CCI-funded nurses, technicians, and co-op students staff these units. CCI also supports clinical research activity in the NICU.
Outpatient Units: A 5-room outpatient center located at 221 Longwood Avenue and a 4-room outpatient center on the 4th floor of the Peter Bent Brigham Building in the main hospital. These two facilities are available to assist investigators with outpatient clinical trials.
Research Coordinator Network (RCNet): The Study Coordinator Pool offers investigators experienced study coordinators to aid with clinical research studies. The Research Development Program (RDP) provides direct support for investigators and study staff in preparing and finalizing clinical research study documents for submission to the Institutional Review Board (IRB) and other regulatory groups.
Metabolic Phenotyping Core: Provides support for weighed research diets on the inpatient and outpatient units.
II. Transformative Technologies and Resources Program (TTRP)
Imaging Core: Currently under development, this core will provide imaging services to the clinical research community.
Ultrasound Core: Located within the Standard Bed Unit, provides ultrasound support for inpatient and outpatient studies.
Genetics Consultation Service: A collaborative program with HPCGG to foster the incorporation of genetics and genomics into clinical practice.
Processing, Analytical, and Translational Core (PATC): Sample processing is supported with space, effort and supplies for clinical investigators at each research site within CCI (Standard Bed Unit, IPM Unit, 221 Longwood, and Clinical Trials Center). Additionally, a menu of research assays are made available to investigators in the CCI-funded CLIA-certified laboratory.
III. Community Research Core
Currently under development, this core will support investigators with community-based research projects.
IV. Biostatistics Core
The Biostatistics core provides statistical reviews for studies applying for use of the program, grant development, and data analysis.
V. Bio-Informatics Service
Informatics support is available to clinical investigators and CCI Staff.
VI. Education
Local training and educational programs, to promote high quality clinical research, are available for study coordinators, physician investigators, and other clinical research staff members.
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